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Engineering Manager, Data and ML Infrastructure



Software Engineering, Other Engineering, Data Science
San Francisco, CA, USA
Posted on Wednesday, May 29, 2024

We are advancing AI to power the future of medicine.

At Unlearn, our purpose is to advance artificial intelligence (AI) to eliminate trial and error in medicine. We are innovating advanced machine learning methods to leverage generative AI in forecasting patient outcomes, starting with the domain of clinical trials. We produce AI-generated digital twins of individual trial participants, enabling smaller and more efficient clinical trials to bring effective medicines to patients sooner.

Our innovative work in AI today will reinvent how AI is applied in medicine tomorrow — and we have a top secret plan for how to get there. We won’t be able to achieve this mission just by applying technologies created by others; the future must be invented.

Unlearn is a technology company, not a biotech company. We use computers, not pipettes. We make and use software, we don’t discover or make drugs. We believe that AI will define the future of medicine, and we aren’t deterred by naysayers or skeptics.

We come from a variety of backgrounds ranging from machine learning to marketing—but regardless of where we come from, Unlearners share some common traits:

  • Unlearners are ambitious; we aren’t intimidated by big, challenging goals.

  • Unlearners are disciplined experimenters; we break down our big goals into smaller chunks and meet as often as necessary to track our velocity and iterate quickly.

  • Unlearners are gritty; we never give up, setbacks just make us try harder.

  • Unlearners are receptive to new ideas; in fact, we hate being stuck with the status quo

  • Unlearners are storytellers; sharing information with each other and with the world is super important, too important to be boring. And, last but not least,

  • Unlearners are team-oriented; we put the mission first, the company second, the team third, and individuals last.

Headquartered in San Francisco, with an additional office in Boston, Unlearn was founded in 2017 by a team of world-class machine learning scientists. We have raised venture capital from top tier investors such as Altimeter, Insight Partners, Radical Ventures, 8VC, DCVC, and DCVC Bio, and recently completed our $50 million Series C in January 2024.

If our purpose and culture resonate with you, we invite you to apply.

The Role

We are looking for a manager to lead a team of Data and ML engineers to enhance Unlearn’s Digital Twin technology. In this high-impact role, you’ll use your experience with the latest Data and ML tools to help us build a platform that is secure, transparent, and traceable, while also enabling speed and flexibility to deploy the results of cutting edge research.

The ideal candidate will have strong technical expertise and outstanding people management skills. We are a tech-first company, and our engineers are the lifeblood of everything we do. Your responsibility will involve fostering a positive team culture that promotes both team growth and the attainment of our business objectives.


  • You will partner closely with Data Science and AI/ML researchers to build the stack that powers Unlearn’s core Data and ML products.

  • You will collaborate with engineering leaders to define high-level technical direction and promote a vibrant culture of engineering excellence.

  • You will lead and inspire a team of software engineers by demonstrating hands-on engineering expertise.

  • You will recruit, grow and coach engineers through regular feedback and provide opportunities to make progress towards their goals.

  • You will contribute to technical decision-making discussions by demonstrating a keen understanding of the tradeoffs required to deliver business objectives.


  • At least 5 years of professional software engineering experience.

  • Experience managing engineers in a fast-paced tech startup.

  • Proven track record of maintaining team environments that are collaborative, empowering, supportive, and challenging.

  • Experience leading infrastructure teams that consistently deliver business impact.

  • Excellent communication, collaboration, and coaching abilities.

  • A desire to build an inclusive and diverse culture.

  • Ability to work in our San Francisco office at least 2 days per week.

  • Bonus: Experience building and innovating in highly regulated industries

Benefits & Perks

  • Generous equity participation

  • 100% company-covered medical, dental, & vision insurance plans

  • 401k plan with generous matching

  • Flexible PTO plus company holidays

  • Annual company-wide break December 24 through January 1

  • Professional development budget to attend conferences or other events

  • Commuter benefits plan

  • Paid Parental Leave

Unlearn is an equal opportunity employer.

At Unlearn, we are committed to building a diverse and inclusive workplace, because inclusion and diversity are essential to achieving our mission. If you’re excited about this role, and your past experience doesn’t align perfectly with every qualification in the job description, we encourage you to apply nevertheless.