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Proteomics Technologies Intern

Plexium

Plexium

San Diego, CA, USA
Posted 6+ months ago
Company Overview
Plexium is a pharmaceutical company focused on developing first-in-class protein degrader therapeutics that go beyond the limitations of bivalent degraders and cereblon molecular glues. Our novel integrated drug discovery platform consists of state-of-the-art medicinal chemistry and DNA-encoded library technologies, ultra-high throughput cell-based screening, deep biological understanding of protein degradation, and extensive proteomics and informatics capabilities. Our integrated platform allows us to discover and develop novel degraders of therapeutically validated proteins for cancer and other important disease areas.
Plexium has a positive, friendly, and collaborative work environment with a culture that values teamwork, initiative, ownership and thoughtful risk-taking in developing innovative solutions to challenging scientific problems. We are committed to fostering innovation at all levels, cross-functional team collaboration, and supporting the growth and development of our team members.
Position Summary
The Proteomics department is seeking an enthusiastic and motivated intern to work in a comprehensive project to map the protein interaction networks of several E3 ligases. This project will provide a valuable learning opportunity for the intern to work on cutting-edge Proteomics technology in one of the most promising drug discovery technologies, targeted protein degradation. In addition, the intern will work alongside our team of experienced scientists and gain hands-on experience in cell biology and proteomics techniques for protein-protein and protein-drug interactions, experimental design, data analysis, and scientific communication. Candidates with previous experience with protein-protein interaction techniques such as proximity-dependent labeling (e.g., BioID, TurboID, APEX) or crosslinking followed by mass spec are highly encouraged to apply.

Essential Job Responsibilities

  • Preparing samples for proteomics experiments to characterize protein-protein interactions in cells.
  • Performing mass spec experiments under the guidance of senior lab members
  • Analyzing and presenting experimental data
  • Maintain accurate records of experimental data and contribute to data analysis
  • Maintain a clean and organized laboratory environment, adhering to safety and sterile techniques
  • Participate in team meetings by presenting and discussing experimental results

Required Skills and Qualifications

  • Currently enrolled undergraduate or master's student in biology, biochemistry, molecular biology, or a related field
  • Working knowledge in standard molecular biology techniques and mammalian cell culture
  • Familiarity with protein biochemistry or proteomics techniques
  • Excellent organizational, communication, and interpersonal skills
  • Strong attention to detail and problem-solving skills
  • Eager to learn new skills and technologies
The Plexium Internship Program offers a pay range based on level of education. The hour commitment per week is 40 hours, Monday through Friday during the summer. Interns will be onboarded as temporary employees and will not be eligible for Plexium's benefits, equity, 401K, or bonus plan.
BS Level $22.50 per hour
MS Level $25 per hour
PhD Level $30 per hour
Notice to third party recruitment agencies: Plexium does not accept unsolicited resumes from recruiters or employment agencies. In the absence of an executed recruitment services agreement, there will be no obligation to any referral compensation or recruiter fee.
In the event a recruiter or agency submits a resume or candidate without an agreement Plexium shall explicitly reserve the right to pursue and hire those candidate(s) without any financial obligation to the recruiter or agency. Any unsolicited resumes, including those submitted to hiring managers, shall be deemed the property of Plexium.