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Project Manager, Cell Therapy Platform

Orca Bio

Orca Bio

Operations
Menlo Park, CA, USA
Posted on Jul 4, 2025
More than one million people in the United States today are fighting blood cancer. While a traditional allogeneic stem cell transplant has been the best hope for many, the transplant itself can prove fatal or lead to serious conditions, such as graft vs. host disease. Orca Bio is a late-stage biotechnology company redefining the transplant process by developing next-generation cell therapies with the goal of providing significantly better survival rates with dramatically fewer risks. With our purified, high-precision investigational cell therapies we hope to not only replace patients' blood and immune systems with healthy ones, but also restore their lives.
Orca Bio is seeking a high-performing, strategic, and execution-oriented Project Manager lead the development, implementation, and evolution of our digital cell therapy ordering and coordination platform. This role will serve as the business owner of the platform during its critical design, development, and launch phase, with direct responsibility for delivering a seamless user experience that enables hospital partners to access our first in class therapy, Orca-T.
As the platform stabilizes, the Project Manager will pivot to work on a portfolio of strategic initiatives across the Product Supply organization—driving operational scalability, cross-functional alignment, and continuous improvement as we prepare for commercial growth.This is a hands-on, cross-functional role ideal for someone who thrives in ambiguity, is eager to learn, and enjoys solving complex operational challenges. You’ll act as a utility player—part project manager, part strategist, part builder, supporting our most critical initiatives from day one.

Essential Duties & Key Responsibilities

  • Cell Therapy Ordering and Coordination Platform
  • Serve as the business lead for the design, development, and implementation of Orca Bio’s digital ordering and coordination platform supporting the commercial launch of Orca-T.
  • Partner closely with the technical team to convey functional requirements, manage development priorities, oversee project timelines, ensure quality, and coordinate platform deployment.
  • Oversee and manage the project budget to ensure alignment with business objectives and resource efficiency.
  • Ensure the order management workflow and patient journey are accurately captured and integrated into the platform, with a focus on meeting key customer needs.
  • Provide input on platform scalability, functionality, and system interfaces, informed by business and customer feedback.
  • Serve as the key liaison across internal functions (e.g., commercial, medical, logistics, manufacturing) to gather and align cross-functional requirements, ensuring accurate development and seamless end-to-end integration.
  • Develop and maintain user-facing documentation and training materials to support internal teams and external partners.
  • Strategic Operations Projects:
  • Following platform roll out, the Project Manager will lead high-impact projects that improve operational effectiveness and enable scale.
  • Partnering with manufacturing and supply teams to enhance capacity planning, slot booking, and real-time visibility tools.
  • Conducting strategic analyses (e.g., U.S. apheresis market assessment) to inform investment decisions and internal infrastructure build-out.
  • Leading cross-functional project teams to design and implement scalable systems,processes, and tools that support commercial readiness.
  • Acting as a trusted thought partner to Product Supply leadership in identifying and solving operational pain points with long-term impact.

Minimum Qualifications

  • 4+ years of experience working in a software development organization, biotech, pharma,healthcare operations, digital health, consulting, or supply chain
  • Bachelor’s degree.
  • Strong analytical skills.
  • Project or program management experience.
  • Ability to translate between business needs and technical execution.
  • Excellent communication and stakeholder management skills; able to influence withoutauthority across levels and functions.
  • Customer-first mindset with experience applying user-centered design principles.
  • Thrives in ambiguity and a fast-paced startup environment with shifting priorities.

Preferred Qualifications

  • Familiarity with digital product development processes (e.g., Agile, Scrum) and tools(e.g., JIRA, Confluence, GitHub).
  • Software development experience.
  • Experience working in regulated environments, especially in cell/gene therapy or advanced biologics.
  • Comfortable operating in a fast-paced, high-growth, demanding environment with a mission-driven culture.
The anticipated annual salary range for this job is based on prior experience in the role/industry, education, location, internal equity, and other job-related factors as permitted by law. For remote-based positions, this range may vary based on your local market. You will also be eligible to receive pre-IPO equity, in addition to medical, dental, and vision benefits, flexible PTO, 401(k) plan, life and accidental death and disability coverage, and parental leave benefits. Other perks include free daily lunches and snacks at our on-site locations.
Who we are
We are driven by a passion for science and compassion for patients. We act with urgency to ensure our treatments are one day accessible to all who need them.
We live by our core values of passion, courage, and integrity. Excellence in our work means the chance to unlock a better quality of life for our patients, and with that comes tremendous responsibility.
We innovate on a path that hasn’t been paved. We embrace an entrepreneurial spirit and take calculated risks to achieve our mission. We aren’t afraid to ask “why not” and challenge the status quo.
We maintain a start-up culture of camaraderie and leadership by example, regardless of title.
We’re proud to be an equal opportunity employer, and recognize that celebrating our differences creates stronger, lasting solutions that better serve our team, our patients and their healthcare providers.
Notice to staffing firms
Orca Bio does not accept resumes from staffing agencies with which we do not have a written agreement and specific engagement for a particular opening. Our employment activities, inquiries and offers are managed through our HR/Talent team, and all candidates are presented through this channel only. We do not accept unsolicited resumes, and we rarely outsource recruitment.