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Lead Clinical Laboratory Scientist

Freenome

Brisbane, CA, USA

USD 79.33-89.18 / hour + Equity

Posted on Oct 16, 2025

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Why join Freenome?

Freenome is a high-growth biotech company developing tests to detect cancer using a standard blood draw. To do this, Freenome uses a multiomics platform that combines tumor and non-tumor signals with machine learning to find cancer in its earliest, most-treatable stages.

Cancer is relentless. This is why Freenome is building the clinical, economic, and operational evidence to drive cancer screening and save lives. Our first screening test is for colorectal cancer (CRC) and advanced adenomas, and it’s just the beginning.

Founded in 2014, Freenome has ~400 employees and continues to grow to match the scope of our ambitions to provide access to better screening and earlier cancer detection.

At Freenome, we aim to impact patients by empowering everyone to prevent, detect, and treat their disease. This, together with our high-performing culture of respect and cross-collaboration, is what motivates us to make every day count.

Become a Freenomer

Do you have what it takes to be a Freenomer? A “Freenomer” is a determined, mission-driven, results-oriented employee fueled by the opportunity to change the landscape of cancer and make a positive impact on patients’ lives. Freenomers bring their diverse experience, expertise, and personal perspective to solve problems and push to achieve what’s possible, one breakthrough at a time.

About this opportunity:

The Lead Clinical Laboratory Scientist (Lead CLS) will perform moderate and high-complexity laboratory testing on study specimens, performing quality control and quality assurance procedures, and comply with all applicable local, state, and federal laboratory requirements. The work requires keeping meticulous and organized records; excellent attention to detail; and the ability to flexibly prioritize multiple tasks and schedules, analysis, and results.

Hours and days may vary depending on operational needs
Standing or sitting for long periods of time may be necessary

The role reports to the Director, Clinical Lab - Proteomics

What you’ll do:

Performing laboratory tests, procedures, and analyses according to the laboratory's standard operating procedures
Reviewing, interpreting, and reporting study results in the company's laboratory information management system (LIMS) as assigned
Performing, reviewing, and documenting laboratory quality control procedures
Independently identifying and leading troubleshooting high-complexity assay problems that adversely affect test performance ensuring timely resolution of complex technical issues
Operating, maintaining, and troubleshooting laboratory equipment
Training existing laboratory personnel in new procedures and training new laboratory personnel
Leading internal and external inspection preparation activities as needed
Collaborating with the Development Team and Automation Team to execute assay improvement experiments, new assay configurations, and validations
Documenting all corrective actions taken when test systems deviate from the laboratory's established performance specifications
Performing and documenting routine preventive maintenance
Preparing reagents required for testing
Reporting all concerns of test quality and/or safety to the laboratory supervisor or safety officer
Leading the execution of assay improvements, new assay configurations, and validation
Writing and reviewing procedures, documents, and forms
Providing assistance to laboratory supervisors, including but not limited to:
Performing administrative duties, including but not limited to review of documents and forms and scheduling
- Delegating tasks and assignments to Clinical Laboratory Scientists (CLSs) and laboratory associates, as needed
- Managing staff schedules based on the number of staff and workload in the absence of a supervisor
- Supervising unlicensed and licensed personnel
- Taking charge of shift communication
- Providing updates to supervisors regarding any issues
- Monitoring and overseeing training schedules for new employees
Performing annual reviews of standard operating procedures and work instructions.
Assisting supervisors with coaching CLSs and laboratory associates, including but not limited to providing guidance and constructive feedback
Assisting the supervisors with the development of the troubleshooting and
decision-making skills of CLSs and laboratory associates
Monitoring data and process status, and proactively reporting abnormalities to the supervisor or initiate appropriate corrective actions as needed
Performing other laboratory duties as assigned
Ensuring consistent compliance with all federal, state, and local regulatory requirements and with all company policies and procedures

Must haves:

Possess a valid California Clinical Laboratory Scientist license
Bachelor of Arts or Science in Biomedical Laboratory Science, Clinical Science or related field
Four to five years of CLS licensed work experience in a clinical laboratory setting
Possess working knowledge of local, state, and federal laboratory regulations

Nice to haves:

Clear understanding of good laboratory practices and regulatory compliance
The ability to prioritize tasks with a high emphasis on quality
Strong organizational skills and meticulous attention to detail
Excellent communication skills
The ability to be a strong team player, with a demonstrated track record of success in a cross-functional team environment

Benefits and additional information:

The US target range of our hourly rate for new hires is $79.33 - $89.18. You will also be eligible to receive pre-IPO equity, cash bonuses, and a full range of medical, financial, and other benefits depending on the position offered. Please note that individual total compensation for this position will be determined at the Company’s sole discretion and may vary based on several factors, including but not limited to, location, skill level, years and depth of relevant experience, and education. We invite you to check out our career page @ freenome.com/job-openings/ for additional company information.

Freenome is proud to be an equal-opportunity employer, and we value diversity. Freenome does not discriminate on the basis of race, color, religion, marital status, age, national origin, ancestry, physical or mental disability, medical condition, pregnancy, genetic information, gender, sexual orientation, gender identity or expression, veteran status, or any other status protected under federal, state, or local law.

Applicants have rights under Federal Employment Laws.

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