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Manufacturing Scientist



South San Francisco, CA, USA
Posted on Thursday, October 5, 2023

Why join Freenome?

Freenome is a high-growth biotech company developing tests to detect cancer using a standard blood draw. To do this, Freenome uses a multiomics platform that combines tumor and non-tumor signals with machine learning to find cancer in its earliest, most-treatable stages.

Cancer is relentless. This is why Freenome is building the clinical, economic, and operational evidence to drive cancer screening and save lives. Our first screening test is for colorectal cancer (CRC) and advanced adenomas, and it’s just the beginning.

Founded in 2014, Freenome has ~500 employees and more than $1.1B in funding from key investors, such as the American Cancer Society, Andreessen Horowitz, Anthem Blue Cross, Bain Capital, Colorectal Cancer Alliance, DCVC, Fidelity, Google Ventures, Kaiser Permanente, Novartis, Perceptive Advisors, RA Capital, Roche, Sands Capital, T. Rowe Price, and Verily.

At Freenome, we aim to impact patients by empowering everyone to prevent, detect, and treat their disease. This, together with our high-performing culture of respect and cross-collaboration, is what motivates us to make every day count.

Become a Freenomer

Do you have what it takes to be a Freenomer? A “Freenomer” is a determined, mission-driven, results-oriented employee fueled by the opportunity to change the landscape of cancer and make a positive impact on patients’ lives. Freenomers bring their diverse experience, expertise, and personal perspective to solve problems and push to achieve what’s possible, one breakthrough at a time.

About this opportunity:

At Freenome, we are seeking a Manufacturing Scientist to help grow the Freenome Manufacturing Technical Transfer team. The ideal candidate has a strong background in scientific principles and process development with a keen attention to detail. This person is responsible for the development and optimization of manufacturing processes for the production of our colorectal cancer in vitro diagnostic (IVD) product. You are passionate about enabling efficient and high-quality manufacturing operations and you will have a significant impact on the continued growth of an organization dedicated to changing the entire landscape of cancer.

The role reports to the Manager, Process Manufacturing.

What you’ll do:

  • Collaborate with R&D teams to translate research findings into scalable and efficient manufacturing processes
  • implement, and optimize production processes, including process scale-up, process characterization, and process validation
  • Actively participate in technology transfer activities from R&D to manufacturing, ensuring a smooth transition of processes, materials, and documentation
  • Collect, analyze, and interpret manufacturing data to identify trends, patterns, and areas for improvement
  • Prepare comprehensive reports, documentation, and WIs (Work Instructions) to ensure process reproducibility and compliance
  • Collaborate with cross-functional teams, including R&D, Quality Assurance, Engineering, and Operations, to ensure alignment on project goals, timelines, and deliverables
  • Communicate effectively across teams to drive continuous improvement initiatives and address any manufacturing-related challenges
  • Ensure manufacturing processes comply with relevant industry regulations, quality standards, and safety guidelines
  • Support internal and external audits, inspections, and regulatory submissions
  • Provide technical training and support to the manufacturing team on new processes, equipment, and technologies

Must haves:

  • Bachelor’s degree with at least 5 years of experience
  • A combination of education and experience will be considered
  • Proven experience in manufacturing process development and optimization within a scientific or industrial setting
  • Strong knowledge of process engineering principles, statistical analysis, and design of experiments (DoE)
  • Excellent project management skills with ability to prioritize competing priorities and achieve program deadlines
  • Strong communication and interpersonal skills and demonstrated ability to collaborate effectively with cross-functional teams
  • Experience performing basic laboratory techniques like pipetting, aliquoting and labeling
  • Working Knowledge of GMP (Good Manufacturing Practices), FDA regulations, ISO 13485
  • Strong problem solving skills and the ability to evaluate processes for failures and design experiments to assess improvements

Nice to haves:

  • Experience with automated Liquid handling such as Hamilton/Tecan
  • Proficiency in data analysis and visualization tools, such as JMP, Minitab, or Excel
  • Knowledge in inventory management and LIMS software
  • Understanding of NGS workflows, cancer biology, and/or genetics
  • Experience with liquid biopsy

Benefits and additional information:

The US target range of our base salary for new hires is $102,000 - $155,000. You will also be eligible to receive pre-IPO equity, cash bonuses, and a full range of medical, financial, and other benefits depending on the position offered. Please note that individual total compensation for this position will be determined at the Company’s sole discretion and may vary based on several factors, including but not limited to, location, skill level, years and depth of relevant experience, and education. We invite you to check out our career page @ for additional company information.

Freenome is proud to be an equal-opportunity employer, and we value diversity. Freenome does not discriminate on the basis of race, color, religion, marital status, age, national origin, ancestry, physical or mental disability, medical condition, pregnancy, genetic information, gender, sexual orientation, gender identity or expression, veteran status, or any other status protected under federal, state, or local law.

Applicants have rights under Federal Employment Laws.