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Senior Scientist - Nonclinical Safety Assessment

AbCellera Biologics

AbCellera Biologics

Vancouver, BC, Canada
Posted on Friday, March 31, 2023

AbCellera is a young, energetic, and rapidly growing tech company with an amazing team that searches, decodes, and analyzes natural immune systems to find antibodies that its partners can develop into drugs to prevent and treat disease. This role offers the exciting opportunity to join one of Canada’s top biotech companies, while growing with a team that believes in collaboration, innovation, and mutual support.

We are seeking an experienced and exceptional individual for the role of Senior Scientist - Nonclinical Safety Assessment. This scientist will help to build out our pharm-tox capabilities and increase confidence in our animal modeling so we can help our partners move faster and with less risk to the clinic. Through close collaboration across the company this role will help identify the best antibodies for the job. The successful scientist will be responsible for nonclinical safety assessment activities from the start of program life cycle and into early clinical development, in close collaboration with our partners and external vendors. We are looking for someone who has a passion for understanding how models can predict responses in humans.

How you might spend your days:

  • Performing nonclinical safety assessment activities throughout all stages of antibody drug development across a wide range of disease areas and indications
  • Assessing and selecting vendors, building relationships with a network of external resources, designing and monitoring nonclinical studies
  • Reviewing, interpreting and integrating nonclinical safety data
  • Preparing nonclinical strategy and safety summaries in support of IND and clinical trial applications
  • Guiding and educating teams, and mentoring individual scientists
  • Collaborating with teams across the company to solve problems, analyze, interpret and communicate data
  • Evaluating new technology and testing new models to better predict human adverse responses
  • Reporting findings to our teams and partners to support data-driven decision making

We'd love to hear from you if:

  • You are genuinely curious, with an interest in discussing innovative ideas in a highly collaborative and face paced environment
  • You are good at communicating scientific and/or technical concepts with an emphasis on application
  • You are comfortable working independently to identify project needs then following that up by collaboratively constructing and implementing solutions
  • You enjoy the teamwork that comes with working on complicated biological questions and building data sets that help to predict the success of therapies

Required Qualifications and Education

  • PhD in Toxicology or related discipline with working knowledge of the drug development process and 8+ years practical work experience in a biopharmaceutical industry environment
  • Demonstrated proficiency in antibody drug development from discovery to mid-stage development
  • Significant experience with authoring/reviewing project plans, study protocols, study reports, and safety summaries to ensure appropriate nonclinical safety datasets are accurately generated and interpreted
  • Ability to perform scientific investigation of fundamental toxicology issues, either through review of the academic literature or empirical drug development experience
  • Understanding of regulatory processes, GLP/ICH and other regulatory guidance documents, and basic knowledge of regulatory toxicology
  • Proven interpersonal skills with the ability to work collaboratively as a member of a cross-functional team

Bonus points if you have:

  • Experience with assessing new and emerging in silico / in vitro technologies to improve human safety prediction for the antibody drug development process
  • Experience with early-stage R&D of immuno-oncology therapeutics

Offers & benefits:

A generous compensation package including an equity stake in AbCellera’s success. Our headquarters are nestled in the heart of Vancouver, Canada - we’ll support you and your family in every way we can to relocate if you haven't had the joy of living in this beautiful area!

About AbCellera:

At AbCellera, we find the next generation of therapeutic antibodies. To succeed, we have created innovative solutions at every step - custom antigen preparation and immunizations, microfluidics, high-throughput imaging, genomics, computation, machine learning and laboratory automation - leaving no stone unturned and revolutionizing how scientists can explore natural antibody diversity and the scale at which they can do it. You’ll join a diverse and multi-disciplinary team of biologists, biochemists, engineers, bioinformaticians, computer scientists and physicists - all working together to bring better therapies to patients. This is life-changing research and you could be a part of it.

We’re a growing company with state-of-the-art discovery tools and the drive to be the best in the industry. This isn’t just about having the best technology. We know we need a world-class team of innovators working together to solve the toughest problems. We look for people with drive and energy. Idealists. People we love and people we trust. This may be unconventional, but it is the key to our success. We’re looking for someone like you to support and organize our efforts along the way.

To apply:

Please submit your application through our website and refer to Job ID 23039 in your cover letter. We apologize in advance, but we receive a large volume of applications and are only able to contact those who are selected for an interview.